Gabriela Martins

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Autism Spectrum Disorders (ASD) are characterized by such core symptoms as repetitive behaviors and restricted interests. The molecular and circuit underpinnings of repetitive behavior dysfunction have remained elusive, but it is assumed that they rely on the same basal ganglia circuits that underlie repetitive behavior control and habit formation. Coordinated activity of striatal circuits are critical for proper action initiation, and movement and reinforcement in dorsolateral striatum. I am interested in investigating changes in striatal organization during repetitive and learned sequences in genetic models of ASD.